This website has been created with reference to the Global Reporting Initiative (GRI) Standards.

General Disclosures

Item	Indicator	Relevant Pages in Value Report 2021	Web
1. Organizational profile
102-1	Name of the organization	105-106	Corporate Information
102-2	Activities, brands, products, and services	103-104	Corporate Information
102-3	Location of headquarters	105-106	Corporate Information
102-4	Location of operations	105-106	Global Presence
102-5	Ownership and legal form	111	Information for Shareholders
102-6	Markets served	95/105-106	Worldwide Group Companies Financial Highlights
102-7	Scale of the organization	93-94/105-106	Corporate Information Financial Highlights
102-8	Information on employees and other workers	93-94/108	ESG Data
102-9	Supply chain	65-66/81-92	Quality & Steady Supply
102-10	Significant changes to the organization and its supply chain	-	History as Pharma Innovator Consolidated Financial Statements and Independent Auditor's Report
102-11	Precautionary Principle or approach	31-34/74	The UN Global Compact Sustainability Management
102-12	External initiatives	34/74	The UN Global Compact SDGs for Daiichi Sankyo Climate Strategy Inclusion & Diversity Participation in the Access Accelerated Initiatives
102-13	Membership of associations	-	Major Trade Associations
2. Strategy
102-14	Statement from senior decision-maker	3-8/37-40/47-49	Message from Our CEO
102-15	Key impacts, risks, and opportunities	3-8/17-36/41-44/74	Materiality Risk Management Climate Strategy Consolidated Financial Statements and Independent Auditor's Report
3. Ethics and integrity
102-16	Values, principles, standards, and norms of behavior	2/29-30/71-72	Mission, Vision, and Values Global Policies Compliance System
102-17	Mechanisms for advice and concerns about ethics	71	Compliance System Characteristics of Daiichi Sankyo’s Corporate Governance
4. Governance
102-18	Governance structure	51-52	Characteristics of Daiichi Sankyo’s Corporate Governance
102-19	Delegating authority	51-52	Characteristics of Daiichi Sankyo’s Corporate Governance Corporate Governance
102-20	Executive-level responsibility for economic, environmental, and social topics	-	Appointment of the head of the Corporate Affairs Division (Executive Officer) as the chairperson at the Corporate Ethics Committee and EHS Management Committee
102-21	Consulting stakeholders on economic, environmental, and social topics	18	Sustainability Management Stakeholder Engagement
102-22	Composition of the highest governance body and its committees	53-53/63-64	Characteristics of Daiichi Sankyo’s Corporate Governance Corporate Governance
102-23	Chair of the highest governance body	47-49	Corporate Governance
102-24	Nominating and selecting the highest governance body	52-54	Corporate Governance
102-25	Conflicts of interest	111	Corporate Governance Global Policies
102-26	Role of highest governance body in setting purpose, values, and strategy	47-49	Corporate Governance
102-27	Collective knowledge of highest governance body	50	Corporate Governance
102-28	Evaluating the highest governance body’s performance	50	Corporate Governance
102-29	Identifying and managing economic, environmental, and social impacts	-	Corporate Governance Materiality Risk Management
102-30	Effectiveness of risk management processes	41	Corporate Governance
102-31	Review of economic, environmental, and social topics	17	Materiality Risk Management EHS Policy & Management System
102-32	Highest governance body’s role in sustainability reporting	After creating the Value Report, it is reviewed and approved by the chairman of the Board, CEO and CFO, and then issued.	-
102-33	Communicating critical concerns	41	Corporate Governance Sustainability Management Risk Management
102-34	Nature and total number of critical concerns	42-44	Risk Management
102-35	Remuneration policies	55	Corporate Governance
102-36	Process for determining remuneration	55-56	Corporate Governance
102-37	Stakeholders’ involvement in remuneration	-	Corporate Governance Information on Ordinary General Meetings of Shareholders
102-38	Annual total compensation ratio	-	-
102-39	Percentage increase in annual total compensation ratio	-	-
5. Stakeholder engagement
102-40	List of stakeholder groups	67-68	Stakeholder Engagement
102-41	Collective bargaining agreements	-	ESG Data
102-42	Identifying and selecting stakeholders	67-68	Stakeholder Engagement
102-43	Approach to stakeholder engagement	18/67-68	Stakeholder Engagement
102-44	Key topics and concerns raised	-	Stakeholder Engagement
6. Reporting practice
102-45	Entities included in the consolidated financial statements	105-106	Consolidated Financial Statements and Independent Auditor's Report
102-46	Defining report content and topic Boundaries	1	Guidelines
102-47	List of material topics	9-10	Daiichi Sankyo’s Value Creation Process Materiality
102-48	Restatements of information	-	N/A
102-49	Changes in reporting	-	N/A
102-50	Reporting period	1	-
102-51	Date of most recent report	Value Report 2021, October 2021	-
102-52	Reporting cycle	annual	annual
102-53	Contact point for questions regarding the report	back cover	Sustainability Promotion Department
102-54	Claims of reporting in accordance with the GRI Standards	-	-
102-55	GRI content index	-	Guidelines
102-56	External assurance	107-109	Assured by a Third Party ESG Data

Material topics for disclosure
Economy

Item	Indicator	Relevant Pages in Value Report 2021	Web
Economic Performance
201-1	Direct economic value generated and distributed	93-102/105-106	Consolidated Financial Statements and Independent Auditor's Report
201-2	Financial implications and other risks and opportunities due to climate change	73-74	Climate Strategy
201-3	Defined benefit plan obligations and other retirement plans	-	Consolidated Financial Statements and Independent Auditor's Report
201-4	Financial assistance received from government	-	Consolidated Financial Statements and Independent Auditor's Report
Indirect Economic Impacts
103-1	Explanation of the material topic and its Boundary	17-18/25-26	Materiality Access to healthcare
103-2	The management approach and its components	25-26	Sustainability Management Access to healthcare Daiichi Sankyo Group Policy on Access to Healthcare
103-3	Evaluation of the management approach	25-26	Access to healthcare Research & Development Availability Capacity Building
203-1	Infrastructure investments and services supported	25-26/69-70	Research & Development Availability Capacity Building
203-2	Significant indirect economic impacts	-	Mobile Healthcare Field Clinic Services in Tanzania Development of Healthcare Workers in China Technical Cooperation regarding MR Vaccine Production in Vietnam
Procurement Practices
204-1	Proportion of spending on local suppliers	-	-
Anti-corruption*
103-1	Explanation of the material topic and its Boundary	17-18/29-30	Materiality Ethics & Compliance
103-2	The management approach and its components	29-30	Global Policies Transparency of Corporate Activities Sustainability Management The UN Global Compact Ethics & Compliance
103-3	Evaluation of the management approach	29-30	Compliance System
205-1	Operations assessed for risks related to corruption	-	-
205-2	Communication and training about anti-corruption policies and procedures	-	The UN Global Compact Compliance System ESG Data
205-3	Confirmed incidents of corruption and actions taken	107	Compliance System

Material topics for disclosure
Environment

Item	Indicator	Relevant Pages in Value Report 2021	Web
Materials
301-1	Materials used by weight or volume	-	-
301-2	Recycled input materials used	-	-
301-3	Reclaimed products and their packaging materials	-	ESG Data Environmental Reporting
Energy
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment Climate Strategy
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System Operational Eco-Efficiency Climate Strategy
103-3	Evaluation of the management approach	27-28	EHS Policy & Management System Operational Eco-Efficiency Environmental Reporting
302-1	Energy consumption within the organization	-	Environmental Reporting
302-2	Energy consumption outside of the organization	-	Environmental Reporting
302-3	Energy intensity	-	-
302-4	Reduction of energy consumption	-	Operational Eco-Efficiency Environmental Reporting
302-5	Reductions in energy requirements of products and services	-	-
Water
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment Climate Strategy
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System Climate Strategy
103-3	Evaluation of the management approach	107	EHS Policy & Management System Climate Strategy Environmental Reporting
303-1	Interactions with water as a shared resource	74	Climate Strategy
303-2	Management of water discharge- related impacts	-	Climate Strategy
303-3	Water withdrawal	107	Climate Strategy Environmental Reporting
303-4	Water discharge	107	Environmental Reporting
303-5	Water consumption	107	Climate Strategy
303-1	Water withdrawal by source	99	Environmental Reporting
303-2	Water sources significantly affected by withdrawal of water	-	Climate Strategy
303-3	Water recycled and reused	-	-
Biodiversity
103-1	Explanation of the material topic and its Boundary	17-18	Materiality The Environment Initiatives for Biodiversity Conservation
103-2	The management approach and its components	73-74	Sustainability Management EHS Policy & Management System Initiatives for Biodiversity Conservation
103-3	Evaluation of the management approach	-	EHS Policy & Management System Initiatives for Biodiversity Conservation Environmental Reporting
304-1	Operational sites owned, leased, managed in, or adjacent to, protected areas and areas of high biodiversity value outside protected areas	-	Initiatives for Biodiversity Conservation
304-2	Significant impacts of activities, products, and services on biodiversity	-	Initiatives for Biodiversity Conservation
304-3	Habitats protected or restored	-	Initiatives for Biodiversity Conservation
304-4	IUCN Red List species and national conservation list species with habitats in areas affected by operations	-	-
Emissions
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment Climate Strategy
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System Operational Eco-Efficiency Climate Strategy
103-3	Evaluation of the management approach	27-28	EHS Policy & Management System Operational Eco-Efficiency Environmental Reporting
305-1	Direct (Scope 1) GHG emission	107	Operational Eco-Efficiency Environmental Reporting
305-2	Energy indirect (Scope 2) GHG emissions	107	Operational Eco-Efficiency Environmental Reporting
305-3	Other indirect (Scope 3) GHG emissions	-	Operational Eco-Efficiency Environmental Data Book 2021
305-4	GHG emissions intensity	-	Operational Eco-Efficiency Environmental Reporting
305-5	Reduction of GHG emissions	73-74	Operational Eco-Efficiency Environmental Reporting
305-6	Emissions of ozone-depleting substances (ODS)	-	-
305-7	Nitrogen oxides (NOX), sulfur oxides (SOX), and other significant air emissions	-	Environmental Risks
Effluents and Waste
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System Waste Management
103-3	Evaluation of the management approach	-	EHS Policy & Management System Environmental Risks Waste Management Environmental Reporting
306-1	Water discharge by quality and destination	107	Environmental Risks
306-2	Waste by type and disposal method	-	Environmental Data Book 2021
306-3	Significant spills	-	Environmental Risks Environmental Reporting
306-4	Transport of hazardous waste	-	Environmental Risks
306-5	Water bodies affected by water discharges and/or runoff	-	Environmental Risks
Environmental Compliance
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment EHS Policy & Management System
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System
103-3	Evaluation of the management approach	107	EHS Policy & Management System Environmental Risks Waste Management
307-1	Non-compliance with environmental laws and regulations	-	-
Supplier Environmental Assessment
103-1	Explanation of the material topic and its Boundary	17-18/27-28	Materiality The Environment Sustainable Procurement
103-2	The management approach and its components	27-28	Sustainability Management EHS Policy & Management System
103-3	Evaluation of the management approach	-	EHS Policy & Management System
308-1	New suppliers that were screened using environmental criteria	-	-
308-2	Negative environmental impacts in the supply chain and actions taken	-	EHS Policy & Management System

Material topics for disclosure
Society

Item	Indicator	Relevant Pages in Value Report 2021	Web
Employment
103-1	Explanation of the material topic and its Boundary	17-18/31-32	Materiality Our Workplace Careers
103-2	The management approach and its components	31-32	Sustainability Management Our Workplace Human Resource Recruitment & Development
103-3	Evaluation of the management approach	31/108	Human Resource Recruitment & Development Inclusion & Diversity ESG Data
401-1	New employee hires and employee turnover	31/108	ESG Data
401-2	Benefits provided to full-time employees that are not provided to temporary or part-time employees	-	-
401-3	Parental leave	-	ESG Data
Labor/Management Relations
402-1	Minimum notice periods regarding operational changes	-	Company Culture
Occupational Health and Safety
103-1	Explanation of the material topic and its Boundary	17-18/78	Materiality Our Workplace
103-2	The management approach and its components	78	Sustainability Management Company Culture Workplace Health, Safety & Welfare
103-3	Evaluation of the management approach	78	Company Culture Workplace Health, Safety & Welfare ESG Data
403-1	Occupational health and safety management system	-	Our Workplace
403-2	Hazard identification, risk assessment, and incident investigation	-	Our Workplace
403-3	Occupational health services	-	Our workplace
403-4	Worker participation, consultation, and communication on occupational health and safety	-	Company Culture
403-5	Worker training on occupational health and safety	-	Our Workplace
403-6	Promotion of worker health	-	Our Workplace
403-7	Prevention and mitigation of occupational health and safety impacts directly linked by business relationships	-	Our Workplace
403-8	Workers covered by an occupational health and safety management system	-	-
403-9	Work-related injuries	-	ESG Data
403-10	Work-related ill health	-	-
403-1	Workers representation in formal joint management–worker health and safety committees	-	-
403-2	Types of injury and rates of injury, occupational diseases, lost days, and absenteeism, and number of work- related fatalities	-	ESG Data
403-3	Workers with high incidence or high risk of diseases related to their occupation	-	-
403-4	Health and safety topics covered in formal agreements with trade unions	-	Company Culture
Training and Education
103-1	Explanation of the material topic and its Boundary	13-16	Materiality Our Workplace
103-2	The management approach and its components	57-58	Sustainability Management Our Workplace Human Resource Recruitment & Development Inclusion & Diversity Company Culture
103-3	Evaluation of the management approach	57-58/100	Human Resource Recruitment & Development Inclusion & Diversity Company Culture
404-1	Average hours of training per year per employee	-	ESG Data
404-2	Programs for upgrading employee skills and transition assistance programs	57-58	Human Resource Recruitment & Development Inclusion & Diversity Company Culture
404-3	Percentage of employees receiving regular performance and career development reviews	-	-
Diversity and Equal Opportunity
103-1	Explanation of the material topic and its Boundary	17-18/31-32	Materiality Our Workplace
103-2	The management approach and its components	31-32	Sustainability Management Our Workplace Inclusion & Diversity
405-1	Diversity of governance bodies and employees	31/108	ESG Data
405-2	Ratio of basic salary and remuneration of women to men	-	-
Human Rights Assessment
103-1	Explanation of the material topic and its Boundary	17-18/79-80	Materiality Ethics & Compliance Respect for Human Rights
103-2	The management approach and its components	79-80	Sustainability Management Ethics & Compliance Compliance System Respect for Human Rights Sustainable Procurement The UN Global Compact
103-3	Evaluation of the management approach	79-80	Compliance System Respect for Human Rights Sustainable Procurement
412-1	Operations that have been subject to human rights reviews or impact assessments	-	-
412-2	Employee training on human rights policies or procedures	79	ESG Data Compliance System Respect for Human Rights The UN Global Compact
412-3	Significant investment agreements and contracts that include human rights clauses or that underwent human rights screening	-	-
Local Communities
103-1	Explanation of the material topic and its Boundary	17-18	Materiality Corporate Citizenship
103-2	The management approach and its components	-	Sustainability Management Stakeholder Engagement Corporate Citizenship
103-3	Evaluation of the management approach	-	Stakeholder Engagement Communication with Local Communities Corporate Citizenship
413-1	Operations with local community engagement, impact assessments, and development programs	-	Capacity Building
413-2	Operations with significant actual and potential negative impacts on local communities	-	Environmental Risks
Supplier Social Assessment*
103-1	Explanation of the material topic and its Boundary	17-18	Materiality Sustainable Procurement
103-2	The management approach and its components	-	Sustainability Management Respect for Human Rights Sustainable Procurement The UN Global Compact
103-3	Evaluation of the management approach	-	Respect for Human Rights Sustainable Procurement
414-1	New suppliers that were screened using social criteria	-	-
414-2	Negative social impacts in the supply chain and actions taken	80	Sustainable Procurement
Public Policy
415-1	Political contributions	-	ESG Data
Customer Health and Safety
103-1	Explanation of the material topic and ts Boundary	17-18/91-92	Materiality Ethics & Compliance Stakeholder Engagement
103-2	The management approach and its components	91-92	Sustainability Management Ethics & Compliance Stakeholder Engagement Communication with Healthcare Professionals and Patients Quality & Steady Supply Clinical Trials Information Disclosure
103-3	Evaluation of the management approach	-	Ethical Marketing Practices Communication with Healthcare Professionals and Patients Quality & Steady Supply ESG Data
416-1	Assessment of the health and safety impacts of product and service categories	-	Clinical Trial Information Disclosure
416-2	Incidents of non-compliance concerning the health and safety impacts of products and services	-	-
Marketing and Labeling
103-1	Explanation of the material topic and ts Boundary	17-18/23-24	Materiality Ethics & Compliance Communication with Healthcare Professionals and Patients
103-2	The management approach and its components	23-24/91	Sustainability Management Ethics & Compliance Stakeholder Engagement Communication with Healthcare Professionals and Patients
103-3	Evaluation of the management approach	23-24	Ethical Marketing Practices Communication with Healthcare Professionals and Patients Clinical Trials Information Disclosure ESG Data
417-1	Requirements for product and service information and labeling	23-24	Ethical Marketing Practices Communication with Healthcare Professionals and Patients
417-2	Incidents of non-compliance concerning product and service information and labeling	-	-
417-3	Incidents of non-compliance concerning marketing communications	-	-
Socioeconomic Compliance*
103-1	Explanation of the material topic and its Boundary	17-18/29-30	Materiality Ethics & Compliance Communication with Healthcare Professionals and Patients
103-2	The management approach and its components	29-30	Sustainability Management Compliance System Respect for Human Rights Information Management & Security
103-3	Evaluation of the management approach	-	Compliance System Respect for Human Rights Information Management & Security Responsible Tax & Financial Reporting
419-1	Non-compliance with laws and regulations in the social and economic rea	-	-